"If sanity and insanity exist, how shall we know them?" -- David Rosenham

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A notable feature of the post-pandemic world has been the brazen way in which global political leaders have continued promoting COVID-19 vaccines as safe. A rare exception in this respect is Slovakia’s Prime Minister Robert Fico, who, in a recent parliamentary speech, admitted that deaths from various cardiovascular events in his country have risen because of the vaccinations.

Mechanisms of severe acute respiratory syndrome coronavirus-2 disease-induced liver injury and their consequences at organ level (left). Severe acute respiratory syndrome coronavirus-2 cellular targets involved in liver damage (center and right). Various factors have been postulated to contribute to liver injury in the context of coronavirus disease 2019 (COVID-19), including direct cytotoxic effects, vascular changes, immunological and inflammatory responses associated with COVID-19, immune responses triggered by COVID-19 vaccination, and drug-induced liver injury.

Republican Texas Attorney General Ken Paxton argued on Wednesday that pharmaceutical company Pfizer lied about the efficacy of the COVID-19 vaccine and the effectiveness could be lower than 10%.